Case studies
Download the R scripts, Mlxtran and pharmML codes used for these case studies
PKPD models and others…
Clinical Trial Simulation
- Individualised therapies
- Comparing several dosage regimens – part I
- Comparing several dosage regimens – part II
- Comparing several dosage regimens – part III
Modelling & Simulation Workflow
We show how simulx can be easily integrated in a workflow: i) modeling is performed first with Monolix, ii) simulation is then performed with Simulx, using the parameters estimated by Monolix
- A PK example
- A PKPD example
- An example with continuous PK and categorical PD data
- An example with continuous PK and repeated events
- Two examples with censored data
- An example with inter occasion variability